E2F1 (pS337) Antibody from ABBEXA LTD
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| Antigenic Specificity | E2F1 (pS337) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S337 of human E2F1. |
| Other Names | E2f, E2F transcription factor, Dmel_CG6376, CG6376, DRTF1/E2F, DmE2F-1, DmelCG6376, Dp, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F-1, E2F1, Evar(3)164, dE2F, dE2F1, def21, drosE2F1, l(3)07172, l(3)j3, e2f1, PBR3, PRB-binding protein E2F-1, RBAP-1, RBBP-3, RBBP3, Retinoblastoma binding protein 3, Retinoblastoma-associated protein 1, Transcription factor E2F1, RBAP1, RBP3, Retinoblastoma-binding protein 3, Transcription factor E2F1E2F-1, E2f, E2f, E2f , E2f , E2F transcription factor, E2F transcription factor, E2F transcription factor , E2F transcription factor , Dmel_CG6376, Dmel_CG6376, Dmel_CG6376 , Dmel_CG6376 , CG6376, CG6376, CG6376 , CG6376 , DRTF1/E2F, DRTF1/E2F, DRTF1/E2F , DRTF1/E2F , DmE2F-1, DmE2F-1, DmE2F-1 , DmE2F-1 , DmelCG6376, DmelCG6376, DmelCG6376 , DmelCG6376 , Dp, Dp, Dp , Dp , E(Sev-CycE)3A, E(Sev-CycE)3A, E(Sev-CycE)3A , E(Sev-CycE)3A , E(var)3-93E, E(var)3-93E, E(var)3-93E , E(var)3-93E , E(var)3-95E, E(var)3-95E, E(var)3-95E , E(var)3 |
| Gene, Accession # | UniProt: Q01094 |
| Catalog # | abx031857 |
| Price | please inquire |
| Order / More Info | E2F1 (pS337) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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