Protein-Tyrosine Kinase 2-Beta (PYK2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Protein-Tyrosine Kinase 2-Beta (PYK2) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK.Entrez Protein NP_004094.It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway.The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity.The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2.The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Four transcript variants encoding two different isoforms have been found for this gene. |
| Immunogen | Purified recombinant fragment of PYK2 (aa815-997) expressed in E. coli. |
| Other Names | CADTK, CAK beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, FADK 2, FAK2, Focal adhesion kinase 2, kinase Pyk2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, PTK2B, RAFTK, Related adhesion focal tyrosine kinase, PYK2, Protein-tyrosine kinase 2-beta, Calcium-regulated non-receptor proline-rich tyrosine kinase, CAK-beta, CAKB, PKB, PTK, FRNK, CADTK, CADTK, CADTK , CADTK , CAK beta, CAK beta, CAK beta , CAK beta , Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase , Calcium-dependent tyrosine kinase , Cell adhesion kinase beta, Cell adhesion kinase beta, Cell adhesion kinase beta , Cell adhesion kinase beta , FADK 2, FADK 2, FADK 2 , FADK 2 , FAK2, FAK2, FAK2 , FAK2 , Focal adhesion kinase 2, Focal adhesion kinase 2, Focal adhesion kinase 2 , Focal adhesion kinase 2 , kinase Pyk2, kinase Pyk2, kinase Pyk2 , kinase Pyk2 , Proline-rich tyrosine kinase 2, Proline-rich tyrosine kinase 2, Proline |
| Gene, Accession # | PTK2B, Gene ID: 2185, UniProt: Q14289 |
| Catalog # | abx016050 |
| Price | please inquire |
| Order / More Info | Protein-Tyrosine Kinase 2-Beta (PYK2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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