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Antigenic Specificity | Proteinase-Activated Receptor 2 / PAR2 (F2RL1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proteinase-Activated Receptor 2 / PAR2 (F2RL1) antibody is a Rabbit polyclonal antibody for the detection of F2RL1. Proteinase-activated receptors (PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, F2RL1, PAR3 and PAR4. F2RL1, also known as F2RL1, is expressed in epithelial cells (e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. F2RL1 knockout mice and F2RL1 agonists and antagonists have implicated F2RL1 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers. (PMID:23895492) |
Immunogen | coagulation factor II(thrombin) receptor-like 1 |
Other Names | F2RL1, F2R Like Trypsin Receptor 1, Coagulation Factor II (Thrombin) Receptor-Like 1, G-Protein Coupled Receptor 11, Thrombin Receptor-Like 1, GPR11, PAR2, Coagulation Factor II Receptor-Like 1, Proteinase-Activated Receptor 2, Proteinase-Activated Receptor-2, Protease-Activated Receptor 2, PAR-2, F2RL1, F2RL1, F2RL1 , F2RL1 , F2R Like Trypsin Receptor 1, F2R Like Trypsin Receptor 1, F2R Like Trypsin Receptor 1 , F2R Like Trypsin Receptor 1 , Coagulation Factor II (Thrombin) Receptor-Like 1, Coagulation Factor II (Thrombin) Receptor-Like 1, Coagulation Factor II (Thrombin) Receptor-Like 1 , Coagulation Factor II (Thrombin) Receptor-Like 1 , G-Protein Coupled Receptor 11, G-Protein Coupled Receptor 11, G-Protein Coupled Receptor 11 , G-Protein Coupled Receptor 11 , Thrombin Receptor-Like 1, Thrombin Receptor-Like 1, Thrombin Receptor-Like 1 , Thrombin Receptor-Like 1 , GPR11, GPR11, GPR11 , GPR11 , PAR2, PAR2, PAR2 , PAR2 , Coagulation Factor II Receptor-Like 1, Coagulation Fact |
Gene, Accession # | F2RL1, Gene ID: 2150, NCBI: NP_005233.3, UniProt: P55085 |
Catalog # | abx240187 |
Price | please inquire |
Order / More Info | Proteinase-Activated Receptor 2 / PAR2 (F2RL1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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