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Antigenic Specificity | Mediator Complex Subunit 14 (MED14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. |
Immunogen | KLH-conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14. |
Other Names | ARC150, Activator-recruited cofactor 150 kDa component, CRSP2, CSP2, Cofactor required for Sp1 transcriptional activation subunit 2, DRIP150, EXLM1, Thyroid hormone receptor-associated protein complex 170 kDa component, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, CXorf4, RGR1, TRAP170, Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14, RGR1 homolog, MED14, mediator complex subunit 14, CRSP complex subunit 2, RGR1 homolog, cofactor required for Sp1 transcriptional activation, subunit 2 (150kD), hRGR1, human homolog of yeast RGR1, thyroid hormone receptor-associated protein complex component TRAP170, vitamin D receptor-interacting protein complex component DRIP150, vitamin D3 receptor-interacting protein complex 150 kDa component, ARC150, ARC150, ARC150 , ARC150 , Activator-recruited cofactor 150 kDa component, Activator-recruited cofactor 150 kDa component, Activator-recruited cofactor 150 kD |
Gene, Accession # | MED14, UniProt: O60244 |
Catalog # | abx026654 |
Price | please inquire |
Order / More Info | Mediator Complex Subunit 14 (MED14) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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