CD59 Glycoprotein (CD59) Antibody from ABBEXA LTD
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| Antigenic Specificity | CD59 Glycoprotein (CD59) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 20 µg, 50 µg, 100 µg, 200 µg+ |
| Concentration | n/a |
| Applications | ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD59 Glycoprotein antibody (HRP) is a Rabbit polyclonal antibody conjugated to HRP against CD59 Glycoprotein. CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex (MAC), whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This inhibitor appears to be species-specific. This protein also plays a role in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59 deficiency results in hemolytic anemia and thrombosis, which can lead to cerebral infarction. |
| Immunogen | Recombinant human CD59 glycoprotein (26-102AA). |
| Other Names | 16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, CD 59, CD59, CD59 antigen, CD59 antigen complement regulatory protein, CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule complement regulatory protein, Cd59a, Complement regulatory protein, EL32, FLJ38134, FLJ92039, G344, HRF 20, HRF-20, HRF20, Human leukocyte antigen MIC11, Ly 6 like protein, Lymphocytic antigen CD59/MEM43, MAC inhibitory protein, MAC IP, MAC-inhibitory protein, MAC-IP, MACIF, MACIP, MEM43, MEM43 antigen, Membrane attack complex (MAC) inhibition factor, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MGC2354, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18 20, PROTECTIN, Surface antigen recognized by monoclonal, T cell activating protein, p18-20, 1F-5Ag, H19, P-18, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC-2.4.1.135, Beta-1,3-glucu |
| Gene, Accession # | CD59, Gene ID: 966, UniProt: P13987 |
| Catalog # | abx108081 |
| Price | please inquire |
| Order / More Info | CD59 Glycoprotein (CD59) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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