Histone H2A.X (H2AFX) Antibody from ABBEXA LTD

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Antigenic SpecificityHistone H2A.X (H2AFX)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size50 µl, 200 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
ImmunogenKLH-conjugated synthetic peptide between 115-143 amino acids from the C-terminal region of human H2AFX.
Other NamesH2A.X, H2A/X, H2AX, Histone H2A.X, H2AFX, H2A.X, H2A.X, H2A.X , H2A.X , H2A/X, H2A/X, H2A/X , H2A/X , H2AX, H2AX, H2AX , H2AX , Histone H2A.X, Histone H2A.X, Histone H2A.X , Histone H2A.X , H2AFX, H2AFX, H2AFX , H2AFX
Gene, Accession #NCBI: NP_002096.1, UniProt: P16104
Catalog #abx034795
Priceplease inquire
Order / More InfoHistone H2A.X (H2AFX) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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