Proteasome Activator Subunit 1 (PSME1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Proteasome Activator Subunit 1 (PSME1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PSME1 antibody is a Rabbit polyclonal antibody against PSME1. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants. |
| Immunogen | Recombinant protein of human PSME1. |
| Other Names | PA28A, IFI5111, REGalpha, PA28alpha, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), PSME1, MGC8628, Proteasome activator complex subunit 1, 11S regulator complex subunit alpha, REG-alpha, Activator of multicatalytic protease subunit 1, Interferon gamma up-regulated I-5111 protein, IGUP I-5111, Proteasome activator 28 subunit alpha, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), 11S regulator complex alpha subunit, 29-kD MCP activator subunit, interferon gamma up-r, PA28A, PA28A, PA28A , PA28A , IFI5111, IFI5111, IFI5111 , IFI5111 , REGalpha, REGalpha, REGalpha , REGalpha , PA28alpha, PA28alpha, PA28alpha , PA28alpha , proteasome (prosome, proteasome (prosome, proteasome (prosome , proteasome (prosome , macropain) activator subunit 1 (PA28 alpha), macropain) activator subunit 1 (PA28 alpha), macropain) activator subunit 1 (PA28 alpha) , macropain) activator subunit 1 (PA28 alpha) , PSME1, PSME1, PSME1 , PSME1 , MGC8628, MGC8628, MGC8628 , MG |
| Gene, Accession # | PSME1, Gene ID: 5720, UniProt: Q06323 |
| Catalog # | abx004099 |
| Price | please inquire |
| Order / More Info | Proteasome Activator Subunit 1 (PSME1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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