Caspase 5 (CASP5) Antibody from ABBEXA LTD

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Antigenic SpecificityCaspase 5 (CASP5)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, FCM
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
ImmunogenKLH-conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
Other NamesCASP5, CASP-5, Caspase 5, Caspase-5, ICE (rel)III, ICEREL-III, ICE (rel)-III, Ich-3, Protease TY, ICH3, Protease ICH-3, TY protease, ICE (rel) III, Caspase-5 subunit p20, Caspase-5 subunit p10, CASP5, CASP5, CASP5 , CASP5 , CASP-5, CASP-5, CASP-5 , CASP-5 , Caspase 5, Caspase 5, Caspase 5 , Caspase 5 , Caspase-5, Caspase-5, Caspase-5 , Caspase-5 , ICE (rel)III, ICE (rel)III, ICE (rel)III , ICE (rel)III , ICEREL-III, ICEREL-III, ICEREL-III , ICEREL-III , ICE (rel)-III, ICE (rel)-III, ICE (rel)-III , ICE (rel)-III , Ich-3, Ich-3, Ich-3 , Ich-3 , Protease TY, Protease TY, Protease TY , Protease TY , ICH3, ICH3, ICH3 , ICH3 , Protease ICH-3, Protease ICH-3, Protease ICH-3 , Protease ICH-3 , TY protease, TY protease, TY protease , TY protease , ICE (rel) III, ICE (rel) III, ICE (rel) III , ICE (rel) III , Caspase-5 subunit p20, Caspase-5 subunit p20, Caspase-5 subunit p20 , Caspase-5 subunit p20 , Caspase-5 subunit p10, Caspase-5 subunit p10, Caspase-5 subunit p10 , Caspase-5
Gene, Accession #UniProt: P51878
Catalog #abx026001
Priceplease inquire
Order / More InfoCaspase 5 (CASP5) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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