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Antigenic Specificity | Caspase 5 (CASP5) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5. |
Other Names | CASP5, CASP-5, Caspase 5, Caspase-5, ICE (rel)III, ICEREL-III, ICE (rel)-III, Ich-3, Protease TY, ICH3, Protease ICH-3, TY protease, ICE (rel) III, Caspase-5 subunit p20, Caspase-5 subunit p10, CASP5, CASP5, CASP5 , CASP5 , CASP-5, CASP-5, CASP-5 , CASP-5 , Caspase 5, Caspase 5, Caspase 5 , Caspase 5 , Caspase-5, Caspase-5, Caspase-5 , Caspase-5 , ICE (rel)III, ICE (rel)III, ICE (rel)III , ICE (rel)III , ICEREL-III, ICEREL-III, ICEREL-III , ICEREL-III , ICE (rel)-III, ICE (rel)-III, ICE (rel)-III , ICE (rel)-III , Ich-3, Ich-3, Ich-3 , Ich-3 , Protease TY, Protease TY, Protease TY , Protease TY , ICH3, ICH3, ICH3 , ICH3 , Protease ICH-3, Protease ICH-3, Protease ICH-3 , Protease ICH-3 , TY protease, TY protease, TY protease , TY protease , ICE (rel) III, ICE (rel) III, ICE (rel) III , ICE (rel) III , Caspase-5 subunit p20, Caspase-5 subunit p20, Caspase-5 subunit p20 , Caspase-5 subunit p20 , Caspase-5 subunit p10, Caspase-5 subunit p10, Caspase-5 subunit p10 , Caspase-5 |
Gene, Accession # | UniProt: P51878 |
Catalog # | abx026001 |
Price | please inquire |
Order / More Info | Caspase 5 (CASP5) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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