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Antigenic Specificity | Tropomyosin 1 (TPM1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TPM1 antibody is a Rabbit polyclonal antibody against TPM1. Tropomyosin-1 (TPM1) belongs to the high molecular weight members of tropomyosin familyThe protein exists in an alpha-helical coiled-coil conformation and binds multiple acting monomers in a tight manner to stabilize and regulate the actin filamentTropomyosins fullfill functions in muscle and non-muscle cellsIn muscle cells, tropomyosins associate with the troponin complex and play a central role in the calcium-dependent regulation of striated muscle contraction in vertebRatesIn non-muscle cells, tropomyosins are implicated in the formation and stabilization of cytoskeletal actin filaments to ensure normal cellular processesMutations of tropomysin-1 have been reported as a cause of dilated cardiac myopathiesTropomyosin-1 also functions as a tumor suppressor, and many malignant tumors demonstRate downregulation of tropomyosin-1 expressionTropomyosin-1 is phosphorylated at Ser283 through the Erk/DAPK pathway, which promotes stress fiber formation in response to oxidative stress. |
Immunogen | Recombinant protein of human TPM1. |
Other Names | CMH3, TMSA, CMD1Y, C15orf13, HTM-alpha, TPM1, CMH3, CMH3, CMH3 , CMH3 , TMSA, TMSA, TMSA , TMSA , CMD1Y, CMD1Y, CMD1Y , CMD1Y , C15orf13, C15orf13, C15orf13 , C15orf13 , HTM-alpha, HTM-alpha, HTM-alpha , HTM-alpha , TPM1, TPM1, TPM1 , TPM1 |
Gene, Accession # | TPM1, Gene ID: 7168, UniProt: P09493 |
Catalog # | abx117045 |
Price | please inquire |
Order / More Info | Tropomyosin 1 (TPM1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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