Tropomyosin 1 (TPM1) Antibody from ABBEXA LTD

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Antigenic SpecificityTropomyosin 1 (TPM1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionTPM1 antibody is a Rabbit polyclonal antibody against TPM1. Tropomyosin-1 (TPM1) belongs to the high molecular weight members of tropomyosin familyThe protein exists in an alpha-helical coiled-coil conformation and binds multiple acting monomers in a tight manner to stabilize and regulate the actin filamentTropomyosins fullfill functions in muscle and non-muscle cellsIn muscle cells, tropomyosins associate with the troponin complex and play a central role in the calcium-dependent regulation of striated muscle contraction in vertebRatesIn non-muscle cells, tropomyosins are implicated in the formation and stabilization of cytoskeletal actin filaments to ensure normal cellular processesMutations of tropomysin-1 have been reported as a cause of dilated cardiac myopathiesTropomyosin-1 also functions as a tumor suppressor, and many malignant tumors demonstRate downregulation of tropomyosin-1 expressionTropomyosin-1 is phosphorylated at Ser283 through the Erk/DAPK pathway, which promotes stress fiber formation in response to oxidative stress.
ImmunogenRecombinant protein of human TPM1.
Other NamesCMH3, TMSA, CMD1Y, C15orf13, HTM-alpha, TPM1, CMH3, CMH3, CMH3 , CMH3 , TMSA, TMSA, TMSA , TMSA , CMD1Y, CMD1Y, CMD1Y , CMD1Y , C15orf13, C15orf13, C15orf13 , C15orf13 , HTM-alpha, HTM-alpha, HTM-alpha , HTM-alpha , TPM1, TPM1, TPM1 , TPM1
Gene, Accession #TPM1, Gene ID: 7168, UniProt: P09493
Catalog #abx117045
Priceplease inquire
Order / More InfoTropomyosin 1 (TPM1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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