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Antigenic Specificity | ABL (pY204) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, IF/ICC, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-ABL protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y204 of human ABL. |
Other Names | ABL, JTK7, Tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150, ABL1, c-ABL, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein Tyrosine kinase, ARG, ABL, ABL, ABL , ABL , JTK7, JTK7, JTK7 , JTK7 , Tyrosine-protein kinase ABL1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase ABL1 , Tyrosine-protein kinase ABL1 , Abelson murine leukemia viral oncogene homolog 1, Abelson murine leukemia viral oncogene homolog 1, Abelson murine leukemia viral oncogene homolog 1 , Abelson murine leukemia viral oncogene homolog 1 , Abelson tyrosine-protein kinase 1, Abelson tyrosine-protein kinase 1, Abelson tyrosine-protein kinase 1 , Abelson tyrosine-protein kinase 1 , Proto-oncogene c-Abl, Proto-oncogene c-Abl, Proto-oncogene c-Abl , Proto-oncogene c-Abl , p150, p150, p150 , p150 , ABL1, ABL1, ABL1 , ABL1 , c-ABL, c-ABL, c-ABL , c-ABL , Abelson murine leukemia viral oncogen |
Gene, Accession # | UniProt: P00519 |
Catalog # | abx032003 |
Price | please inquire |
Order / More Info | ABL (pY204) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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