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Antigenic Specificity | Serine/Threonine-Protein Kinase PINK1, Mitochondrial (PINK1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD. |
Immunogen | KLH-conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6). |
Other Names | BRPK, PARK6, PINK1, PTEN induced putative kinase 1, PTEN-induced putative kinase, Protein kinase BRPK, FLJ27236, serine/threonine-protein kinase PINK1, Serine/threonine-protein kinase PINK1 mitochondrial, PTEN-induced putative kinase protein 1, mitochondrial, BRPK, BRPK, BRPK , BRPK , PARK6, PARK6, PARK6 , PARK6 , PINK1, PINK1, PINK1 , PINK1 , PTEN induced putative kinase 1, PTEN induced putative kinase 1, PTEN induced putative kinase 1 , PTEN induced putative kinase 1 , PTEN-induced putative kinase, PTEN-induced putative kinase, PTEN-induced putative kinase , PTEN-induced putative kinase , Protein kinase BRPK, Protein kinase BRPK, Protein kinase BRPK , Protein kinase BRPK , FLJ27236, FLJ27236, FLJ27236 , FLJ27236 , serine/threonine-protein kinase PINK1, serine/threonine-protein kinase PINK1, serine/threonine-protein kinase PINK1 , serine/threonine-protein kinase PINK1 , Serine/threonine-protein kinase PINK1 mitochondrial, Serine/threonine-protein kinase PINK1 mitochondrial, S |
Gene, Accession # | PINK1, NCBI: NP_115785.1, UniProt: Q9BXM7 |
Catalog # | abx032823 |
Price | please inquire |
Order / More Info | Serine/Threonine-Protein Kinase PINK1, Mitochondrial (PINK1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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