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Antigenic Specificity | PKN beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K. |
Immunogen | KLH-conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human PKN beta. |
Other Names | PKN3, PKNBETA, Serine/threonine-protein kinase N3, Protein kinase PKN-beta, Protein-kinase C-related kinase 3, PKN3, PKN3, PKN3 , PKN3 , PKNBETA, PKNBETA, PKNBETA , PKNBETA , Serine/threonine-protein kinase N3, Serine/threonine-protein kinase N3, Serine/threonine-protein kinase N3 , Serine/threonine-protein kinase N3 , Protein kinase PKN-beta, Protein kinase PKN-beta, Protein kinase PKN-beta , Protein kinase PKN-beta , Protein-kinase C-related kinase 3, Protein-kinase C-related kinase 3, Protein-kinase C-related kinase 3 , Protein-kinase C-related kinase 3 |
Gene, Accession # | UniProt: Q6P5Z2 |
Catalog # | abx033775 |
Price | please inquire |
Order / More Info | PKN beta Antibody from ABBEXA LTD |
Product Specific References | n/a |
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