Edit |   |
---|---|
Antigenic Specificity | RAC-Gamma Serine/threonine-Protein Kinase (Akt3) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3), with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease. |
Immunogen | Purified recombinant fragment of Akt3 expressed in E. Coli. |
Other Names | AKT Serine/Threonine Kinase 3, RAC-PK-Gamma, PKB Gamma, STK-2, PKBG, V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B Gamma), V-Akt Murine Thymoma Viral Oncogene Homolog 3, RAC-Gamma Serine/Threonine Protein Kinase, RAC-Gamma Serine/Threonine-Protein Kinase, Protein Kinase B Gamma, Protein Kinase Akt-3, PKB-GAMMA, RAC-Gamma, MPPH2, PRKBG, MPPH, V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma), Protein Kinase B, Gamma, AKT3, DKFZP434N0250, serine threonine protein kinase, Akt-3, AKT Serine/Threonine Kinase 3, AKT Serine/Threonine Kinase 3, AKT Serine/Threonine Kinase 3 , AKT Serine/Threonine Kinase 3 , RAC-PK-Gamma, RAC-PK-Gamma, RAC-PK-Gamma , RAC-PK-Gamma , PKB Gamma, PKB Gamma, PKB Gamma , PKB Gamma , STK-2, STK-2, STK-2 , STK-2 , PKBG, PKBG, PKBG , PKBG , V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B Gamma), V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B Gamma), V-Akt Murine Thymoma Viral Oncogene Homolog |
Gene, Accession # | AKT3, Gene ID: 10000, UniProt: Q9Y243 |
Catalog # | abx010372 |
Price | please inquire |
Order / More Info | RAC-Gamma Serine/threonine-Protein Kinase (Akt3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950