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Antigenic Specificity | Nuclear Factor NF-Kappa-B P105 Subunit (NFKB1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear Factor NF-Kappa-B P105 Subunit (NFKB1) antibody is a Mouse monoclonal antibody for the detection of NFKB1. This gene encodes a 105 kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kDa protein. The 105 kDa protein is a Rel protein-specific transcription inhibitor and the 50 kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. |
Immunogen | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
Other Names | NFKB1, Nuclear Factor Kappa B Subunit 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, DNA-Binding Factor KBF1, EBP-1, Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor NF-Kappa-B P105 Subunit, Nuclear Factor NF-Kappa-B P50 Subunit, NF-Kappabeta, NF-Kappa-B, NF-KappaB, NFKB1, NFKB1, NFKB1 , NFKB1 , Nuclear Factor Kappa B Subunit 1, Nuclear Factor Kappa B Subunit 1, Nuclear Factor Kappa B Subunit 1 , Nuclear Factor Kappa B Subunit 1 , Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 , Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 , DNA-Binding Factor KBF1, DNA-Binding Factor KBF1, DNA-Binding Factor KBF1 , DNA-Binding Factor KBF1 , EBP-1, EBP-1, EBP-1 , EBP-1 , Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor Kappa- |
Gene, Accession # | NFKB1, Gene ID: 4790, UniProt: P19838 |
Catalog # | abx240011 |
Price | please inquire |
Order / More Info | Nuclear Factor NF-Kappa-B P105 Subunit (NFKB1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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