Nuclear Factor NF-Kappa-B P105 Subunit (NFKB1) Antibody from ABBEXA LTD

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Antigenic SpecificityNuclear Factor NF-Kappa-B P105 Subunit (NFKB1)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
FormatProtein A purified
Size100 µg,
Concentration2 mg/ml
ApplicationsELISA, WB, IF/ICC
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DescriptionNuclear Factor NF-Kappa-B P105 Subunit (NFKB1) antibody is a Mouse monoclonal antibody for the detection of NFKB1.

This gene encodes a 105 kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kDa protein. The 105 kDa protein is a Rel protein-specific transcription inhibitor and the 50 kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Immunogennuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Other NamesNFKB1, Nuclear Factor Kappa B Subunit 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, DNA-Binding Factor KBF1, EBP-1, Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor NF-Kappa-B P105 Subunit, Nuclear Factor NF-Kappa-B P50 Subunit, NF-Kappabeta, NF-Kappa-B, NF-KappaB, NFKB1, NFKB1, NFKB1 , NFKB1 , Nuclear Factor Kappa B Subunit 1, Nuclear Factor Kappa B Subunit 1, Nuclear Factor Kappa B Subunit 1 , Nuclear Factor Kappa B Subunit 1 , Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 , Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 , DNA-Binding Factor KBF1, DNA-Binding Factor KBF1, DNA-Binding Factor KBF1 , DNA-Binding Factor KBF1 , EBP-1, EBP-1, EBP-1 , EBP-1 , Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor Kappa-B DNA Binding Subunit, Nuclear Factor Kappa-
Gene, Accession #NFKB1, Gene ID: 4790, UniProt: P19838
Catalog #abx240011
Priceplease inquire
Order / More InfoNuclear Factor NF-Kappa-B P105 Subunit (NFKB1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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