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Antigenic Specificity | Glutamate Metabotropic Receptor 7 (GRM7) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 240-269 amino acids from the N-terminal region of human GRM7. |
Other Names | GLUR7, GPRC1G, metabotropic glutamate receptor 7, mGlu7, MGR7, GRM7, glutamate receptor, metabotropic 7, FLJ40498, MGLUR7, GLUR7, GLUR7, GLUR7 , GLUR7 , GPRC1G, GPRC1G, GPRC1G , GPRC1G , metabotropic glutamate receptor 7, metabotropic glutamate receptor 7, metabotropic glutamate receptor 7 , metabotropic glutamate receptor 7 , mGlu7, mGlu7, mGlu7 , mGlu7 , MGR7, MGR7, MGR7 , MGR7 , GRM7, GRM7, GRM7 , GRM7 , glutamate receptor, metabotropic 7, glutamate receptor, metabotropic 7, glutamate receptor, metabotropic 7 , glutamate receptor, metabotropic 7 , FLJ40498, FLJ40498, FLJ40498 , FLJ40498 , MGLUR7, MGLUR7, MGLUR7 , MGLUR7 |
Gene, Accession # | UniProt: Q14831 |
Catalog # | abx029192 |
Price | please inquire |
Order / More Info | Glutamate Metabotropic Receptor 7 (GRM7) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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