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Antigenic Specificity | Myc Proto-Oncogene Protein (MYC) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 5 µg, 20 µg, 100 µg, |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myc Proto-Oncogene Protein (MYC) antibody is a mouse monoclonal antibody against Myc Proto-Oncogene Protein (MYC). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, in human. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini, in human and mouse. Under conditions of stress, such as high cell densities and methionine deprivation, there is a specific and dramatic increase in the synthesis of the non-AUG initiated protein, suggesting its importance in times of adversity. Alternative splicing results in multiple transcript variants. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | abx137743 |
Price | please inquire |
Order / More Info | Myc Proto-Oncogene Protein (MYC) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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