Edit |   |
---|---|
Antigenic Specificity | Oxysterols Receptor LXR-Alpha (NR1H3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements. |
Immunogen | KLH-conjugated synthetic peptide between 226-253 amino acids from the Central region of human NR1H3. |
Other Names | LXR-a, LXRA, RLD-1, NR1H3, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3, LXR-a, LXR-a, LXR-a , LXR-a , LXRA, LXRA, LXRA , LXRA , RLD-1, RLD-1, RLD-1 , RLD-1 , NR1H3, NR1H3, NR1H3 , NR1H3 , Oxysterols receptor LXR-alpha, Oxysterols receptor LXR-alpha, Oxysterols receptor LXR-alpha , Oxysterols receptor LXR-alpha , Liver X receptor alpha, Liver X receptor alpha, Liver X receptor alpha , Liver X receptor alpha , Nuclear receptor subfamily 1 group H member 3, Nuclear receptor subfamily 1 group H member 3, Nuclear receptor subfamily 1 group H member 3 , Nuclear receptor subfamily 1 group H member 3 |
Gene, Accession # | UniProt: Q13133 |
Catalog # | abx034585 |
Price | please inquire |
Order / More Info | Oxysterols Receptor LXR-Alpha (NR1H3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950