Ecdysoneless Homolog (Drosophila) (ECD) Antibody from ABBEXA LTD
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| Antigenic Specificity | Ecdysoneless Homolog (Drosophila) (ECD) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ecdysoneless Homolog (Drosophila) (ECD) antibody is a Rabbit polyclonal antibody for the detection of ECD. Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle-regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212). |
| Immunogen | ecdysoneless homolog(Drosophila) |
| Other Names | ECD, GCR2, HSGT1, Protein ecdysoneless homolog, Protein SGT1, SGT1, Suppressor of GCR2, ECD, ECD, ECD , ECD , GCR2, GCR2, GCR2 , GCR2 , HSGT1, HSGT1, HSGT1 , HSGT1 , Protein ecdysoneless homolog, Protein ecdysoneless homolog, Protein ecdysoneless homolog , Protein ecdysoneless homolog , Protein SGT1, Protein SGT1, Protein SGT1 , Protein SGT1 , SGT1, SGT1, SGT1 , SGT1 , Suppressor of GCR2, Suppressor of GCR2, Suppressor of GCR2 , Suppressor of GCR2 |
| Gene, Accession # | Gene ID: 11319, UniProt: O95905 |
| Catalog # | abx240104 |
| Price | please inquire |
| Order / More Info | Ecdysoneless Homolog (Drosophila) (ECD) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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