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Antigenic Specificity | Tyrosine-Protein Kinase Receptor UFO (AXL) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduce signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants. |
Immunogen | Purified recombinant fragment of AXL (aa466-530) expressed in E. Coli. |
Other Names | AXL, AXL oncogene, UFO, Ark, Tyrosine-protein kinase receptor UFO, Adhesion-related kinase, AXL transforming sequence/gene, Oncogene AXL, AXL receptor tyrosine kinase, JTK11, Tyro7, AXL, AXL, AXL , AXL , AXL oncogene, AXL oncogene, AXL oncogene , AXL oncogene , UFO, UFO, UFO , UFO , Ark, Ark, Ark , Ark , Tyrosine-protein kinase receptor UFO, Tyrosine-protein kinase receptor UFO, Tyrosine-protein kinase receptor UFO , Tyrosine-protein kinase receptor UFO , Adhesion-related kinase, Adhesion-related kinase, Adhesion-related kinase , Adhesion-related kinase , AXL transforming sequence/gene, AXL transforming sequence/gene, AXL transforming sequence/gene , AXL transforming sequence/gene , Oncogene AXL, Oncogene AXL, Oncogene AXL , Oncogene AXL , AXL receptor tyrosine kinase, AXL receptor tyrosine kinase, AXL receptor tyrosine kinase , AXL receptor tyrosine kinase , JTK11, JTK11, JTK11 , JTK11 , Tyro7, Tyro7, Tyro7 , Tyro7 |
Gene, Accession # | AXL, Gene ID: 558, UniProt: P30530 |
Catalog # | abx011796 |
Price | please inquire |
Order / More Info | Tyrosine-Protein Kinase Receptor UFO (AXL) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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