Signal Transducer And Activator of Transcription 3 (STAT3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Signal Transducer And Activator of Transcription 3 (STAT3) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, monkey |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development.Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities.Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding.Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways.Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3a (86 kDa) and Stat3 beta (79 kDa) depend on cell type, ligand exposure or cell maturation stage.It is notable that Stat3 beta lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.Tissue specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Immunogen | Purified recombinant fragment of human STAT3 expressed in E. coli. |
| Other Names | Signal transducer and activator of transcription 3, STAT3, APRF, DNA-Binding Protein APRF, ADMIO, HIES, Acute-Phase Response Factor, Signal transducer and activator of transcription 3, STAT3, APRF, DNA-Binding Protein APRF, ADMIO, HIES, Acute-Phase Response Factor, signal transducer and activator of transcription 3 (acute-phase response factor), FLJ20882, MGC16063, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3 , Signal transducer and activator of transcription 3 , STAT3, STAT3, STAT3 , STAT3 , APRF, APRF, APRF , APRF , DNA-Binding Protein APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF , DNA-Binding Protein APRF , ADMIO, ADMIO, ADMIO , ADMIO , HIES, HIES, HIES , HIES , Acute-Phase Response Factor, Acute-Phase Response Factor, Acute-Phase Response Factor , Acute-Phase Response Factor , Signal transducer and activator of transcription 3, Signal transducer and acti |
| Gene, Accession # | Gene ID: 6774 |
| Catalog # | abx016002 |
| Price | please inquire |
| Order / More Info | Signal Transducer And Activator of Transcription 3 (STAT3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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