Emopamil Binding Protein (Sterol Isomerase) (EBP) Antibody from ABBEXA LTD

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Antigenic SpecificityEmopamil Binding Protein (Sterol Isomerase) (EBP)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionThe protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
ImmunogenKLH-conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.
Other NamesCholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, D8-D7 sterol isomerase, Emopamil-binding protein, EBP, 3-beta-hydroxysteroid-Delta (8), Delta (7) isomerase, Delta (8) Delta (7) sterol isomerase, Cholestenol Delta-isomerase, Cholestenol Delta-isomerase, Cholestenol Delta-isomerase , Cholestenol Delta-isomerase , Delta(8)-Delta(7) sterol isomerase, Delta(8)-Delta(7) sterol isomerase, Delta(8)-Delta(7) sterol isomerase , Delta(8)-Delta(7) sterol isomerase , D8-D7 sterol isomerase, D8-D7 sterol isomerase, D8-D7 sterol isomerase , D8-D7 sterol isomerase , Emopamil-binding protein, Emopamil-binding protein, Emopamil-binding protein , Emopamil-binding protein , EBP, EBP, EBP , EBP , 3-beta-hydroxysteroid-Delta (8), 3-beta-hydroxysteroid-Delta (8), 3-beta-hydroxysteroid-Delta (8) , 3-beta-hydroxysteroid-Delta (8) , Delta (7) isomerase, Delta (7) isomerase, Delta (7) isomerase , Delta (7) isomerase , Delta (8) Delta (7) sterol isomerase, Delta (8) Delta (7) sterol isome
Gene, Accession #UniProt: Q15125
Catalog #abx031142
Priceplease inquire
Order / More InfoEmopamil Binding Protein (Sterol Isomerase) (EBP) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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