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Antigenic Specificity | Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | 2 mg/ml |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells. |
Immunogen | KLH-conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2. |
Other Names | ERN2, endoplasmic reticulum to nucleus signaling 2, IRE1b, ER to nucleus signalling 2, IRE1 beta, IRE1, S. cerevisiae, homolog of, endoplasmic reticulum to nucleus signalling 2, inositol-requiring 1 beta, IRE2, Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, Serine/threonine-protein kinase, Endoribonuclease, ERN2, ERN2, ERN2 , ERN2 , endoplasmic reticulum to nucleus signaling 2, endoplasmic reticulum to nucleus signaling 2, endoplasmic reticulum to nucleus signaling 2 , endoplasmic reticulum to nucleus signaling 2 , IRE1b, IRE1b, IRE1b , IRE1b , ER to nucleus signalling 2, ER to nucleus signalling 2, ER to nucleus signalling 2 , ER to nucleus signalling 2 , IRE1 beta, IRE1 beta, IRE1 beta , IRE1 beta , IRE1, S. cerevisiae, homolog of, IRE1, S. cerevisiae, homolog of, IRE1, S. cerevisiae, homolog of , IRE1, S. cerevisiae, homolog of , endoplasmic reticulum to nucleus signalling 2, endopl |
Gene, Accession # | Gene ID: 10595, UniProt: Q76MJ5 |
Catalog # | abx033192 |
Price | please inquire |
Order / More Info | Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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