Peroxisome Proliferator Activated Receptor Delta (PPARD) Antibody from ABBEXA LTD
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| Antigenic Specificity | Peroxisome Proliferator Activated Receptor Delta (PPARD) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. |
| Immunogen | KLH-conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human PPARD. |
| Other Names | PPARD, peroxisome proliferator activated receptor delta, peroxisome proliferator-activated receptor delta, PPAR-beta, PPAR-delta, nuclear hormone receptor 1, nuclear receptor subfamily 1 group C member 2, peroxisome proliferator-activated nuclear receptor beta/delta variant 2, peroxisome proliferator-activated receptor beta, FAAR, NR1C2, NUC1, NUCI, PPARB, PPARd/B, PPARD, PPARD, PPARD , PPARD , peroxisome proliferator activated receptor delta, peroxisome proliferator activated receptor delta, peroxisome proliferator activated receptor delta , peroxisome proliferator activated receptor delta , peroxisome proliferator-activated receptor delta, peroxisome proliferator-activated receptor delta, peroxisome proliferator-activated receptor delta , peroxisome proliferator-activated receptor delta , PPAR-beta, PPAR-beta, PPAR-beta , PPAR-beta , PPAR-delta, PPAR-delta, PPAR-delta , PPAR-delta , nuclear hormone receptor 1, nuclear hormone receptor 1, nuclear hormone receptor 1 , nuclear hor |
| Gene, Accession # | NCBI: NP_001165289.1, NP_001165290.1, NP_001165291.1, NP_006229.1, NP_803184.1, UniProt: Q03181 |
| Catalog # | abx027601 |
| Price | please inquire |
| Order / More Info | Peroxisome Proliferator Activated Receptor Delta (PPARD) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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