Centaurin-Gamma-1 (CENTG1) Antibody from ABBEXA LTD

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Antigenic SpecificityCentaurin-Gamma-1 (CENTG1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionGTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1) dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
ImmunogenKLH-conjugated synthetic peptide between 850-877 amino acids from the C-terminal region of human CENTG1.
Other NamesAGAP2, CENTG1, KIAA0167, Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, Centaurin-gamma-1, GTP-binding and GTPase-activating protein 2, Phosphatidylinositol 3-kinase enhancer, AGAP2, AGAP2, AGAP2 , AGAP2 , CENTG1, CENTG1, CENTG1 , CENTG1 , KIAA0167, KIAA0167, KIAA0167 , KIAA0167 , Arf-GAP with GTPase, Arf-GAP with GTPase, Arf-GAP with GTPase , Arf-GAP with GTPase , ANK repeat and PH domain-containing protein 2, ANK repeat and PH domain-containing protein 2, ANK repeat and PH domain-containing protein 2 , ANK repeat and PH domain-containing protein 2 , Centaurin-gamma-1, Centaurin-gamma-1, Centaurin-gamma-1 , Centaurin-gamma-1 , GTP-binding and GTPase-activating protein 2, GTP-binding and GTPase-activating protein 2, GTP-binding and GTPase-activating protein 2 , GTP-binding and GTPase-activating protein 2 , Phosphatidylinositol 3-kinase enhancer, Phosphatidylinositol 3-kinase enhancer, Phosphatidylinositol 3-kinase enhancer , Phosphatidylinositol 3-kinase en
Gene, Accession #AGAP2, UniProt: Q99490
Catalog #abx026003
Priceplease inquire
Order / More InfoCentaurin-Gamma-1 (CENTG1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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