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Antigenic Specificity | Superoxide Dismutase [Mn], Mitochondrial (SOD2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOD2 antibody is a Rabbit polyclonal antibody against SOD2. The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anionThe SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrixUnlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrionROS are implicated in a wide range of degeneRative processes, including Alzheimer's disease, Parkinson's disease and ischemic heart diseaseHomozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiRatory chain deficiencies in heart and skeletal musclePolymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans. |
Immunogen | Recombinant protein of human SOD2. |
Other Names | SOD2, IPOB, MNSOD, MVCD6, Superoxide dismutase [Mn], mitochondrial, Superoxide dismutase [Mn] mitochondrial, superoxide dismutase 2 mitochondrial, IPO-B, Mn-SOD, SOD2, SOD2, SOD2 , SOD2 , IPOB, IPOB, IPOB , IPOB , MNSOD, MNSOD, MNSOD , MNSOD , MVCD6, MVCD6, MVCD6 , MVCD6 , Superoxide dismutase [Mn], Superoxide dismutase [Mn], Superoxide dismutase [Mn] , Superoxide dismutase [Mn] , mitochondrial, mitochondrial, mitochondrial , mitochondrial , Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase [Mn] mitochondrial , Superoxide dismutase [Mn] mitochondrial , superoxide dismutase 2 mitochondrial, superoxide dismutase 2 mitochondrial, superoxide dismutase 2 mitochondrial , superoxide dismutase 2 mitochondrial , IPO-B, IPO-B, IPO-B , IPO-B , Mn-SOD, Mn-SOD, Mn-SOD , Mn-SOD |
Gene, Accession # | SOD2, Gene ID: 6648, UniProt: P04179 |
Catalog # | abx117084 |
Price | please inquire |
Order / More Info | Superoxide Dismutase [Mn], Mitochondrial (SOD2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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