Flap Structure Specific Endonuclease 1 (FEN1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Flap Structure Specific Endonuclease 1 (FEN1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Flap Structure Specific Endonuclease 1 (FEN1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FEN1 antibody is a Rabbit polyclonal antibody against FEN1. The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. |
| Immunogen | Recombinant protein of human FEN1. |
| Other Names | FEN1, FEN-1, MF1, RAD2, Flap endonuclease 1, DNase IV, Flap structure-specific endonuclease 1, Maturation factor 1, hFEN-1, FEN1, FEN1, FEN1 , FEN1 , FEN-1, FEN-1, FEN-1 , FEN-1 , MF1, MF1, MF1 , MF1 , RAD2, RAD2, RAD2 , RAD2 , Flap endonuclease 1, Flap endonuclease 1, Flap endonuclease 1 , Flap endonuclease 1 , DNase IV, DNase IV, DNase IV , DNase IV , Flap structure-specific endonuclease 1, Flap structure-specific endonuclease 1, Flap structure-specific endonuclease 1 , Flap structure-specific endonuclease 1 , Maturation factor 1, Maturation factor 1, Maturation factor 1 , Maturation factor 1 , hFEN-1, hFEN-1, hFEN-1 , hFEN-1 |
| Gene, Accession # | FEN1, Gene ID: 2237, UniProt: P39748 |
| Catalog # | abx001089 |
| Price | please inquire |
| Order / More Info | Flap Structure Specific Endonuclease 1 (FEN1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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