Mitochondrial Antiviral Signaling Protein (MAVS) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Mitochondrial Antiviral Signaling Protein (MAVS) antibody, protein, ELISA kits.
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| Antigenic Specificity | Mitochondrial Antiviral Signaling Protein (MAVS) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mitochondrial Antiviral Signaling Protein (MAVS) antibody is a Rabbit polyclonal antibody for the detection of MAVS. Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.It can undergoe phosphorylation on multiple sites and ubiquitination, which may together cause the molecular weight migrate to about 70 kDa despite the predicated 57 kDa. |
| Immunogen | mitochondrial antiviral signaling protein |
| Other Names | IPS1, KIAA1271, VISA, Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Putative NF-kappa-B-activating protein 031N, Virus-induced-signaling adapter, IPS1, IPS1, IPS1 , IPS1 , KIAA1271, KIAA1271, KIAA1271 , KIAA1271 , VISA, VISA, VISA , VISA , Mitochondrial antiviral-signaling protein, Mitochondrial antiviral-signaling protein, Mitochondrial antiviral-signaling protein , Mitochondrial antiviral-signaling protein , MAVS, MAVS, MAVS , MAVS , CARD adapter inducing interferon beta, CARD adapter inducing interferon beta, CARD adapter inducing interferon beta , CARD adapter inducing interferon beta , Cardif, Cardif, Cardif , Cardif , Interferon beta promoter stimulator protein 1, Interferon beta promoter stimulator protein 1, Interferon beta promoter stimulator protein 1 , Interferon beta promoter stimulator protein 1 , IPS-1, IPS-1, IPS-1 , IPS-1 , Putative NF-kappa-B-activating prot |
| Gene, Accession # | MAVS, Gene ID: 57506, UniProt: Q7Z434 |
| Catalog # | abx240064 |
| Price | please inquire |
| Order / More Info | Mitochondrial Antiviral Signaling Protein (MAVS) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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