Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) antibody, protein, ELISA kits.
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| Antigenic Specificity | Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 20 µg, 50 µg, 100 µg, 200 µg+ |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ERBB2 antibody (FITC) is a Rabbit polyclonal antibody conjugated to FITC against ERBB2. ERBB2 is a protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. It is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. It regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. |
| Immunogen | Recombinant human Receptor tyrosine-protein kinase erbB-2 protein (153-598AA). |
| Other Names | C-erbB-2, Epidermal growth factor receptor-related protein, ErbB2, HER2, MLN 19, NEU, NEU proto-oncogene, NGL, Receptor protein-tyrosine kinase erbB-2, Receptor protein-tyrosine kinase erbB-2 precursor, Tyrosine kinase-type cell surface receptor HER2, kinase ErbB2, p185erbB2, Epidermal Growth Factor Receptor 2, EGFR2, CD340 Antigen, HER-2/Neu, Herstatin, CD340, HER-2, MLN19, TKR1, C-Erb B2/Neu Protein, HER 2, erbb2, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Kiaa3023, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), human epidermal growth factor receptor 2, C-erbB-2, C-erbB-2, C-erbB-2 , C-erbB-2 , Epidermal growth factor receptor-related protein, Epidermal growth factor receptor-related protein, Epidermal growth factor receptor-related protein , Epidermal growth factor receptor-related protein , ErbB2, ErbB2, ErbB2 , ErbB2 , HER2, HER2, H |
| Gene, Accession # | ERBB2, Gene ID: 2064, NCBI: NP_001005862.1, NM_001005862.2, UniProt: P04626 |
| Catalog # | abx107283 |
| Price | please inquire |
| Order / More Info | Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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