MAP3K7IP1-S423 Antibody from ABBEXA LTD
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|---|---|
| Antigenic Specificity | MAP3K7IP1-S423 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. |
| Immunogen | KLH-conjugated synthetic peptide between 401-430 amino acids from human MAP3K7IP1. |
| Other Names | TAB1, MAP3K7IP1, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, TGF-beta-activated kinase 1-binding protein 1, TAB1, TAB1, TAB1 , TAB1 , MAP3K7IP1, MAP3K7IP1, MAP3K7IP1 , MAP3K7IP1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , TGF-beta-activated kinase 1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1 , TGF-beta-activated kinase 1-binding protein 1 |
| Gene, Accession # | UniProt: Q15750 |
| Catalog # | abx033028 |
| Price | please inquire |
| Order / More Info | MAP3K7IP1-S423 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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