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Antigenic Specificity | ER Lumen Protein-Retaining Receptor 1 (KDELR1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. |
Immunogen | KLH-conjugated synthetic peptide between 185-211 amino acids from the C-terminal region of human KDELR1. |
Other Names | KDELR1, ERD2.1, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention receptor 1, Putative MAPK-activating protein PM23, KDELR1, KDELR1, KDELR1 , KDELR1 , ERD2.1, ERD2.1, ERD2.1 , ERD2.1 , ER lumen protein retaining receptor 1, ER lumen protein retaining receptor 1, ER lumen protein retaining receptor 1 , ER lumen protein retaining receptor 1 , KDEL endoplasmic reticulum protein retention receptor 1, KDEL endoplasmic reticulum protein retention receptor 1, KDEL endoplasmic reticulum protein retention receptor 1 , KDEL endoplasmic reticulum protein retention receptor 1 , Putative MAPK-activating protein PM23, Putative MAPK-activating protein PM23, Putative MAPK-activating protein PM23 , Putative MAPK-activating protein PM23 |
Gene, Accession # | KDELR1, UniProt: P24390 |
Catalog # | abx030790 |
Price | please inquire |
Order / More Info | ER Lumen Protein-Retaining Receptor 1 (KDELR1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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