Toll Like Receptor Adaptor Molecule 1 (TICAM1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Toll Like Receptor Adaptor Molecule 1 (TICAM1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. |
| Immunogen | KLH-conjugated synthetic peptide between 115-143 amino acids from the N-terminal region of human TICAM1. |
| Other Names | TICAM1, PRVTIRB, TRIF, TIR domain-containing adapter molecule 1, Proline-rich, vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, TICAM-1, TICAM1, TICAM1, TICAM1 , TICAM1 , PRVTIRB, PRVTIRB, PRVTIRB , PRVTIRB , TRIF, TRIF, TRIF , TRIF , TIR domain-containing adapter molecule 1, TIR domain-containing adapter molecule 1, TIR domain-containing adapter molecule 1 , TIR domain-containing adapter molecule 1 , Proline-rich, Proline-rich, Proline-rich , Proline-rich , vinculin and TIR domain-containing protein B, vinculin and TIR domain-containing protein B, vinculin and TIR domain-containing protein B , vinculin and TIR domain-containing protein B , Putative NF-kappa-B-activating protein 502H, Putative NF-kappa-B-activating protein 502H, Putative NF-kappa-B-activating protein 502H , Putative NF-kappa-B-activating protein 502H , Toll-interleukin-1 receptor doma |
| Gene, Accession # | TICAM1, NCBI: NP_891549.1, UniProt: Q8IUC6 |
| Catalog # | abx034891 |
| Price | please inquire |
| Order / More Info | Toll Like Receptor Adaptor Molecule 1 (TICAM1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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