Alpha Actinin 4 (ACTN4) Antibody from ABBEXA LTD

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Antigenic SpecificityAlpha Actinin 4 (ACTN4)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This protein is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and is thought to be involved in metastatic processes. Mutations in the gene encoding this protein have been associated with focal and segmental glomerulosclerosis.
ImmunogenKLH-conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human ACTN4.
Other NamesACTN4, ACTININ-4, Actinin, alpha 4, Actinin alpha4 isoform, FSGS1, F-actin cross-linking protein, Non-muscle alpha-actinin 4, Alpha-actinin-4, FSGS, ACTN4, ACTN4, ACTN4 , ACTN4 , ACTININ-4, ACTININ-4, ACTININ-4 , ACTININ-4 , Actinin, Actinin, Actinin , Actinin , alpha 4, alpha 4, alpha 4 , alpha 4 , Actinin alpha4 isoform, Actinin alpha4 isoform, Actinin alpha4 isoform , Actinin alpha4 isoform , FSGS1, FSGS1, FSGS1 , FSGS1 , F-actin cross-linking protein, F-actin cross-linking protein, F-actin cross-linking protein , F-actin cross-linking protein , Non-muscle alpha-actinin 4, Non-muscle alpha-actinin 4, Non-muscle alpha-actinin 4 , Non-muscle alpha-actinin 4 , Alpha-actinin-4, Alpha-actinin-4, Alpha-actinin-4 , Alpha-actinin-4 , FSGS, FSGS, FSGS , FSGS
Gene, Accession #ACTN4, UniProt: O43707
Catalog #abx033682
Priceplease inquire
Order / More InfoAlpha Actinin 4 (ACTN4) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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