Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody from ABBEXA LTD

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Antigenic SpecificityFibroblast Growth Factor Receptor 1 (FGFR1)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionThe protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome. The genomic organization of this gene is very similar to family members 2-4, encompassing 19 exons that are subject to complex alternative splicing, which allows for structural, tissue expression and ligand affinity variations among the isoforms.
ImmunogenPurified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.
Other NamesFGFR1, Fibroblast Growth Factor Receptor 1, Basic Fibroblast Growth Factor Receptor 1, Fms-Related Tyrosine Kinase 2, Proto-Oncogene C-Fgr, BFGF-R-1, FGFR-1, N-SAM, BFGFR, FGFBR, FLT-2, HBGFR, FLT2, CEK, FLG, Heparin-Binding Growth Factor Receptor, Hydroxyaryl-Protein Kinase, FMS-Like Tyrosine Kinase 2, FGFR1/PLAG1 Fusion, Pfeiffer Syndrome, CD331 Antigen, HRTFDS, CD331, ECCL, KAL2, HH2, OGD, FLT2, KAL2, BFGFR, N-SAM,Basic Fibroblast Growth Factor Receptor 1, Fms-Related Tyrosine Kinase-2, FLJ99988, OTTHUMP00000190875, OTTHUMP00000190876, OTTHUMP00000190880, basic fibroblast growth fa, MFR, H2, H3, H4, H5, C-FGR, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), FLG protein, N-sam tyrosine kinase, tyrosylprotein kinase, protein-tyrosine kinase, FMS-like tyrosine, Proto-oncogene c-Fg, FGFR1, FGFR1, FGFR1 , FGFR1 , Fibroblast Growth Factor Receptor 1, Fibroblast Growth Factor Receptor 1, Fibroblast Growth Factor Receptor 1 , Fibroblast Growth Facto
Gene, Accession #FGFR1, Gene ID: 2260, UniProt: P11362
Catalog #abx011769
Priceplease inquire
Order / More InfoFibroblast Growth Factor Receptor 1 (FGFR1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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