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Antigenic Specificity | IL2RA/CD25 (Basiliximab biosimilar) |
Clone | monoclonal |
Host Species | Chimeric Human/Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A/G purified |
Size | 100 µg, 1 mg, |
Concentration | typically between 0.5-2.0 mg/ml. |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Basiliximab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL2RA/CD25, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha. Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor. This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney. |
Immunogen | n/a |
Other Names | Basiliximab, IL2RA/CD25, 179045-86-4 |
Gene, Accession # | CAS: 179045-86-4 |
Catalog # | abx831062 |
Price | please inquire |
Order / More Info | IL2RA/CD25 (Basiliximab biosimilar) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950