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Antigenic Specificity | Protein-Tyrosine Kinase 2-Beta (Ptk2b) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 672-701 amino acids from the Central region of mouse Ptk2b. |
Other Names | Ptk2b, Fak2, Pyk2, Raftk, Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, Ptk2b, Ptk2b, Ptk2b , Ptk2b , Fak2, Fak2, Fak2 , Fak2 , Pyk2, Pyk2, Pyk2 , Pyk2 , Raftk, Raftk, Raftk , Raftk , Protein-tyrosine kinase 2-beta, Protein-tyrosine kinase 2-beta, Protein-tyrosine kinase 2-beta , Protein-tyrosine kinase 2-beta , Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase , Calcium-dependent tyrosine kinase , Calcium-regulated non-receptor proline-rich tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase , Calcium-regulated non-receptor proline-rich tyrosine kinase , Cell adhesion kinase beta, Cell adhesion kinase beta, Cell adhesion kinase beta , Ce |
Gene, Accession # | UniProt: Q9QVP9 |
Catalog # | abx027934 |
Price | please inquire |
Order / More Info | Protein-Tyrosine Kinase 2-Beta (Ptk2b) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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