PRAK Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-PRAK antibody, protein, ELISA kits.
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| Antigenic Specificity | PRAK |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PRAK (p38-regulated/activated kinase), also referred to as mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK)-5, is an ubiquitously expressed serine/threonine kinase regulated by p38 alpha and p38 beta MAP kinases. Activated JNK, p38 gamma or p38 delta are unable to induce phosphorylation of PRAK in vitro. Phosphorylation of PRAK occurs in vivo in response to p38 activation by stress-related extracellular stimuli including UV light, oxidation and proinflammatory cytokines. Two other substrates for p38, MAPKAPK-2 and MAPKAPK-3/3pK, share approximately 45% sequence homology with PRAK including the phosphorylation motif recognized by p38, Lys-X-Thr-Pro. Activated PRAK has been shown to specifically phosphorylate HSP 27 in vitro, suggesting that the protein may play a role in stress-induced small heat shock protein phosphorylation in vivo. |
| Immunogen | Purified recombinant fragment of PRAK expressed in E. Coli. |
| Other Names | MAPKAPK5, PRAK, MAP kinase-activated protein kinase 5, p38-regulated/activated protein kinase, MAPKAPK5, MAPKAPK5 , MAPKAPK5 , MAPKAPK5, PRAK, PRAK , PRAK , PRAK, MAP kinase-activated protein kinase 5, MAP kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5, p38-regulated/activated protein kinase, p38-regulated/activated protein kinase , p38-regulated/activated protein kinase , p38-regulated/activated protein kinase |
| Gene, Accession # | MAPKAPK5, Gene ID: 8550, UniProt: Q8IW41 |
| Catalog # | abx011374 |
| Price | please inquire |
| Order / More Info | PRAK Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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