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Antigenic Specificity | Mitogen-Activated Protein Kinase 8 / JNK1 (MAPK8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAPK8 antibody is a Rabbit polyclonal antibody against MAPK8. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen | Recombinant protein of human MAPK8. |
Other Names | MAPK8, Mitogen-Activated Protein Kinase 8, Stress-Activated Protein Kinase 1c, C-Jun N-Terminal Kinase 1, JUN N-Terminal Kinase, MAP Kinase 8, EC 2.7.11.24, JNK-46, SAPK1c, PRKM8, SAPK1, JNK1, Mitogen-Activated Protein Kinase 8 Isoform JNK1 Alpha1, Mitogen-Activated Protein Kinase 8 Isoform JNK1 Beta2, Stress-Activated Protein Kinase JNK1, Stress-Activated Protein Kinase 1, JNK21B1/2, EC 2.7.11, JNK1A2, MAPK 8, JNK, MAPK8/JNK1, JNK1/MAPK8, JNK-1, JNK 1, MAPK8, MAPK8, MAPK8 , MAPK8 , Mitogen-Activated Protein Kinase 8, Mitogen-Activated Protein Kinase 8, Mitogen-Activated Protein Kinase 8 , Mitogen-Activated Protein Kinase 8 , Stress-Activated Protein Kinase 1c, Stress-Activated Protein Kinase 1c, Stress-Activated Protein Kinase 1c , Stress-Activated Protein Kinase 1c , C-Jun N-Terminal Kinase 1, C-Jun N-Terminal Kinase 1, C-Jun N-Terminal Kinase 1 , C-Jun N-Terminal Kinase 1 , JUN N-Terminal Kinase, JUN N-Terminal Kinase, JUN N-Terminal Kinase , JUN N-Terminal Kinase , MAP Kinase |
Gene, Accession # | MAPK8, Gene ID: 5599, UniProt: P45983 |
Catalog # | abx000671 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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