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Antigenic Specificity | SH-PTP2 (SHP2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
Immunogen | Recombinant protein encoding human SHP2. |
Other Names | BPTP3, CFC, MGC14433, NS1, protein tyrosine phosphatase, non-receptor type 11, protein tyrosine phosphatase-2, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, SH-PTP2, SH-PTP3, SHP-2, Shp2, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, BPTP3, BPTP3, BPTP3 , BPTP3 , CFC, CFC, CFC , CFC , MGC14433, MGC14433, MGC14433 , MGC14433 , NS1, NS1, NS1 , NS1 , protein tyrosine phosphatase, protein tyrosine phosphatase, protein tyrosine phosphatase , protein tyrosine phosphatase , non-receptor type 11, non-receptor type 11, non-receptor type 11 , non-receptor type 11 , protein tyrosine phosphatase-2, protein tyrosine phosphatase-2, protein tyrosine phosphatase-2 , protein tyrosine phosphatase-2 , Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 1D , Protein-tyrosine phosphatase 1D , Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase |
Gene, Accession # | UniProt: Q06124 |
Catalog # | abx033966 |
Price | please inquire |
Order / More Info | SH-PTP2 (SHP2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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