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Antigenic Specificity | Casein Kinase 2-Interacting Protein 1 (CKIP-1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CKIP-1 plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). This protein may function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). It appears to target ATM to the plasma membrane and appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. |
Immunogen | KLH-conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human CKIP-1. |
Other Names | PLEKHO1, CKIP1, Pleckstrin homology domain-containing family O member 1, C-Jun-binding protein, Casein kinase 2-interacting protein 1, Osteoclast maturation-associated gene 120 protein, PLEKHO1, PLEKHO1, PLEKHO1 , PLEKHO1 , CKIP1, CKIP1, CKIP1 , CKIP1 , Pleckstrin homology domain-containing family O member 1, Pleckstrin homology domain-containing family O member 1, Pleckstrin homology domain-containing family O member 1 , Pleckstrin homology domain-containing family O member 1 , C-Jun-binding protein, C-Jun-binding protein, C-Jun-binding protein , C-Jun-binding protein , Casein kinase 2-interacting protein 1, Casein kinase 2-interacting protein 1, Casein kinase 2-interacting protein 1 , Casein kinase 2-interacting protein 1 , Osteoclast maturation-associated gene 120 protein, Osteoclast maturation-associated gene 120 protein, Osteoclast maturation-associated gene 120 protein , Osteoclast maturation-associated gene 120 protein |
Gene, Accession # | UniProt: Q53GL0 |
Catalog # | abx033969 |
Price | please inquire |
Order / More Info | Casein Kinase 2-Interacting Protein 1 (CKIP-1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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