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Antigenic Specificity | Ral Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis. |
Immunogen | KLH-conjugated synthetic peptide between 98-125 amino acids from the N-terminal region of human RGL4. |
Other Names | RGL4, RGR, Ral-GDS-related protein, Ral guanine nucleotide dissociation stimulator-like 4, RGL4, RGL4, RGL4 , RGL4 , RGR, RGR, RGR , RGR , Ral-GDS-related protein, Ral-GDS-related protein, Ral-GDS-related protein , Ral-GDS-related protein , Ral guanine nucleotide dissociation stimulator-like 4, Ral guanine nucleotide dissociation stimulator-like 4, Ral guanine nucleotide dissociation stimulator-like 4 , Ral guanine nucleotide dissociation stimulator-like 4 |
Gene, Accession # | RGL4, UniProt: Q8IZJ4 |
Catalog # | abx029646 |
Price | please inquire |
Order / More Info | Ral Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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