Ral Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4) Antibody from ABBEXA LTD

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Antigenic SpecificityRal Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionRal GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis.
ImmunogenKLH-conjugated synthetic peptide between 98-125 amino acids from the N-terminal region of human RGL4.
Other NamesRGL4, RGR, Ral-GDS-related protein, Ral guanine nucleotide dissociation stimulator-like 4, RGL4, RGL4, RGL4 , RGL4 , RGR, RGR, RGR , RGR , Ral-GDS-related protein, Ral-GDS-related protein, Ral-GDS-related protein , Ral-GDS-related protein , Ral guanine nucleotide dissociation stimulator-like 4, Ral guanine nucleotide dissociation stimulator-like 4, Ral guanine nucleotide dissociation stimulator-like 4 , Ral guanine nucleotide dissociation stimulator-like 4
Gene, Accession #RGL4, UniProt: Q8IZJ4
Catalog #abx029646
Priceplease inquire
Order / More InfoRal Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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