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Antigenic Specificity | Chymotrypsin Like Elastase Family Member 3B (CELA3B) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. |
Immunogen | KLH-conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B. |
Other Names | CELA3B, Chymotrypsin Like Elastase Family Member 3B, Cholesterol-Binding Pancreatic Protease, Pancreatic Endopeptidase E, Elastase 3B, Pancreatic, Elastase IIIB, Proteinase E, Elastase-3B, Protease E, ELA3B, Elastase 3B, Chymotrypsin-Like Elastase Family, Member 3B, Chymotrypsin-Like Elastase Family Member 3B, Pancreatic Elastase, Fecal Elastase, EC 3.4.21.70, Elastase 3B, EC 3.4.21, CBPP, CELA3B, CELA3B, CELA3B , CELA3B , Chymotrypsin Like Elastase Family Member 3B, Chymotrypsin Like Elastase Family Member 3B, Chymotrypsin Like Elastase Family Member 3B , Chymotrypsin Like Elastase Family Member 3B , Cholesterol-Binding Pancreatic Protease, Cholesterol-Binding Pancreatic Protease, Cholesterol-Binding Pancreatic Protease , Cholesterol-Binding Pancreatic Protease , Pancreatic Endopeptidase E, Pancreatic Endopeptidase E, Pancreatic Endopeptidase E , Pancreatic Endopeptidase E , Elastase 3B, Pancreatic, Elastase 3B, Pancreatic, Elastase 3B, Pancreatic , Elastase 3B, Pancreatic , Elas |
Gene, Accession # | CELA3B, UniProt: P08861 |
Catalog # | abx027596 |
Price | please inquire |
Order / More Info | Chymotrypsin Like Elastase Family Member 3B (CELA3B) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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