Activin A Receptor Type IB Antibody from ABBEXA LTD
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| Antigenic Specificity | Activin A Receptor Type IB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. The gene for ACVR1B (activin A type IB receptor) is composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed. |
| Immunogen | KLH-conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human Activin A Receptor Type IB (ACVR1B). |
| Other Names | ACVR1B, ACVRLK4, ALK4, Activin receptor type-1B, Activin receptor type IB, Activin receptor-like kinase 4, Serine/threonine-protein kinase receptor R2, ACVR1B, ACVR1B, ACVR1B , ACVR1B , ACVRLK4, ACVRLK4, ACVRLK4 , ACVRLK4 , ALK4, ALK4, ALK4 , ALK4 , Activin receptor type-1B, Activin receptor type-1B, Activin receptor type-1B , Activin receptor type-1B , Activin receptor type IB, Activin receptor type IB, Activin receptor type IB , Activin receptor type IB , Activin receptor-like kinase 4, Activin receptor-like kinase 4, Activin receptor-like kinase 4 , Activin receptor-like kinase 4 , Serine/threonine-protein kinase receptor R2, Serine/threonine-protein kinase receptor R2, Serine/threonine-protein kinase receptor R2 , Serine/threonine-protein kinase receptor R2 |
| Gene, Accession # | UniProt: P36896 |
| Catalog # | abx033689 |
| Price | please inquire |
| Order / More Info | Activin A Receptor Type IB Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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