Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) antibody, protein, ELISA kits.
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| Antigenic Specificity | Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SLAM-like tyrosine-based motif. The conserved arginine residue thought to be essential for sialic acid binding in other SIGLECs is replaced by a glutamine in SLGS and by a cysteine in SLGL. RT-PCR analysis detected high expression of both variants in spleen and small intestine, and SLGS was highly expressed in adrenal gland and SLGL was highly expressed in bone marrow. |
| Immunogen | KLH-conjugated synthetic peptide between 407-438 amino acids from the C-terminal region of human SIGLEC7 (D-siglec). |
| Other Names | ITGB2, CD18, MFI7, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Complement receptor C3 subunit beta, p75, QA79, AIRM1, CD328, CDw328, D-siglec, SIGLEC-7, SIGLECP2, SIGLEC19P, p75/AIRM1, Sialic acid-binding Ig-like lectin 7, Adhesion inhibitory receptor molecule 1, AIRM-1, QA79 membrane protein, SIGLEC7, ITGB2, ITGB2, ITGB2 , ITGB2 , CD18, CD18, CD18 , CD18 , MFI7, MFI7, MFI7 , MFI7 , Integrin beta-2, Integrin beta-2, Integrin beta-2 , Integrin beta-2 , Cell surface adhesion glycoproteins LFA-1/CR3/p150, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Cell surface adhesion glycoproteins LFA-1/CR3/p150 , Cell surface adhesion glycoproteins LFA-1/CR3/p150 , 95 subunit beta, 95 subunit beta, 95 subunit beta , 95 subunit beta , Complement receptor C3 subunit beta, Complement receptor C3 subunit beta, Complement receptor C3 subunit beta , Complement receptor C3 subunit beta , p75, p75, p75 , p75 , QA79, QA79, QA79 , QA79 , AIRM1, AIRM1, |
| Gene, Accession # | UniProt: Q9Y286 |
| Catalog # | abx025089 |
| Price | please inquire |
| Order / More Info | Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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