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Antigenic Specificity | DNA Methyltransferase 3 Beta (Dnmt3b) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. |
Immunogen | KLH-conjugated synthetic peptide between 389-417 amino acids from human Dnmt3b. |
Other Names | DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB, DNMT3B, DNA (cytosine-5) methyltransferase 3B, ICF, ICF1, DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3B , DNA (cytosine-5)-methyltransferase 3B , DNA methyltransferase HsaIIIB, DNA methyltransferase HsaIIIB, DNA methyltransferase HsaIIIB , DNA methyltransferase HsaIIIB , DNA MTase HsaIIIB, DNA MTase HsaIIIB, DNA MTase HsaIIIB , DNA MTase HsaIIIB , M.HsaIIIB, M.HsaIIIB, M.HsaIIIB , M.HsaIIIB , DNMT3B, DNMT3B, DNMT3B , DNMT3B , DNA (cytosine-5) methyltransferase 3B, DNA (cytosine-5) methyltransferase 3B, DNA (cytosine-5) methyltransferase 3B , DNA (cytosine-5) methyltransferase 3B , ICF, ICF, ICF , ICF , ICF1, ICF1, ICF1 , ICF1 |
Gene, Accession # | NCBI: NP_001193984.1, NP_001193985.1, NP_008823.1, NP_787044.1, NP_787045.1, NP_787046.1, UniProt: Q9UBC3 |
Catalog # | abx025686 |
Price | please inquire |
Order / More Info | DNA Methyltransferase 3 Beta (Dnmt3b) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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