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Antigenic Specificity | TGFB Induced Factor Homeobox 1 (TGIF1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. |
Immunogen | KLH-conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human TGIF1. |
Other Names | Homeobox protein TGIF1, 5'-TG-3'-interacting factor 1, TGIF1, TGIF, 5'-tg-3' interacting factor, 5-TG-3 interacting factor, 5-TG-3-interacting factor 1, Homeobox protein TGIF, HPE4, TGFB-induced factor homeobox 1, Homeobox protein TGIF1, Homeobox protein TGIF1, Homeobox protein TGIF1 , Homeobox protein TGIF1 , 5'-TG-3'-interacting factor 1, 5'-TG-3'-interacting factor 1, 5'-TG-3'-interacting factor 1 , 5'-TG-3'-interacting factor 1 , TGIF1, TGIF1, TGIF1 , TGIF1 , TGIF, TGIF, TGIF , TGIF , 5'-tg-3' interacting factor, 5'-tg-3' interacting factor, 5'-tg-3' interacting factor , 5'-tg-3' interacting factor , 5-TG-3 interacting factor, 5-TG-3 interacting factor, 5-TG-3 interacting factor , 5-TG-3 interacting factor , 5-TG-3-interacting factor 1, 5-TG-3-interacting factor 1, 5-TG-3-interacting factor 1 , 5-TG-3-interacting factor 1 , Homeobox protein TGIF, Homeobox protein TGIF, Homeobox protein TGIF , Homeobox protein TGIF , HPE4, HPE4, HPE4 , HPE4 , TGFB-induced factor homeobox 1, |
Gene, Accession # | UniProt: Q15583 |
Catalog # | abx028149 |
Price | please inquire |
Order / More Info | TGFB Induced Factor Homeobox 1 (TGIF1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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