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Antigenic Specificity | HER4 (pY1284) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HER4 (pY1284) Antibody is a Rabbit Polyclonal antibody against HER4 (pY1284). This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1284 of human HER4. |
Other Names | ERBB4, HER4, kinase ErbB4, p180erbB4, MGC138404, ERBB4, ERBB4, ERBB4, ERBB4, HER4, HER4, HER4, HER4, kinase ErbB4, kinase ErbB4, kinase ErbB4, kinase ErbB4, p180erbB4, p180erbB4, p180erbB4, p180erbB4, MGC138404, MGC138404, MGC138404, MGC138404 |
Gene, Accession # | ERBB4, Gene ID: 2066, UniProt: Q15303 |
Catalog # | abx000119 |
Price | please inquire |
Order / More Info | HER4 (pY1284) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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