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Antigenic Specificity | Serine/threonine-Protein Kinase NLK (NLK) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NLK antibody is a Rabbit polyclonal antibody against NLK. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both Thr-183 and Tyr-185 is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine (5,6). Nlk, or nemo-like kinase, is a murine homolog of the Drosophila nemo (nmo) gene. Nlk and Nmo have sequence homology to both the ERK MAP kinases and the cyclin dependent kinases. Nlk is a nuclear protein with the ability to autophosphorylate. |
Immunogen | Recombinant protein of human NLK. |
Other Names | NLK, LAK1, Nemo-like kinase, Nmo kinase, Nemo like kinase, Protein LAK1, DKFZp761G1211, FLJ21033, Serine/threonine-protein kinase NLK, NLK, NLK, NLK , NLK , LAK1, LAK1, LAK1 , LAK1 , Nemo-like kinase, Nemo-like kinase, Nemo-like kinase , Nemo-like kinase , Nmo kinase, Nmo kinase, Nmo kinase , Nmo kinase , Nemo like kinase, Nemo like kinase, Nemo like kinase , Nemo like kinase , Protein LAK1, Protein LAK1, Protein LAK1 , Protein LAK1 , DKFZp761G1211, DKFZp761G1211, DKFZp761G1211 , DKFZp761G1211 , FLJ21033, FLJ21033, FLJ21033 , FLJ21033 , Serine/threonine-protein kinase NLK, Serine/threonine-protein kinase NLK, Serine/threonine-protein kinase NLK , Serine/threonine-protein kinase NLK |
Gene, Accession # | NLK, Gene ID: 51701, UniProt: Q9UBE8 |
Catalog # | abx002290 |
Price | please inquire |
Order / More Info | Serine/threonine-Protein Kinase NLK (NLK) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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