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Antigenic Specificity | Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Immunogen | KLH-conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human ACVRL1. |
Other Names | ACVRL1, Activin A Receptor Like Type 1, Serine/Threonine-Protein Kinase Receptor R3, Activin A Receptor Type II-Like 1, TGF-B Superfamily Receptor Type I, Activin Receptor-Like Kinase 1, Activin A Receptor Type IL, EC 2.7.11.30, ACVRLK1, ALK-1, TSR-I, ALK1, SKR3, Activin A Receptor, Type II-Like Kinase 1, EC 2.7.11, HHT2, ORW2, HHT, ACVRL1, ACVRL1, ACVRL1 , ACVRL1 , Activin A Receptor Like Type 1, Activin A Receptor Like Type 1, Activin A Receptor Like Type 1 , Activin A Receptor Like Type 1 , Serine/Threonine-Protein Kinase Receptor R3, Serine/Threonine-Protein Kinase Receptor R3, Serine/Threonine-Protein Kinase Receptor R3 , Serine/Threonine-Protein Kinase Receptor R3 , Activin A Receptor Type II-Like 1, Activin A Receptor Type II-Like 1, Activin A Receptor Type II-Like 1 , Activin A Receptor Type II-Like 1 , TGF-B Superfamily Receptor Type I, TGF-B Superfamily Receptor Type I, TGF-B Superfamily Receptor Type I , TGF-B Superfamily Receptor Type I , Activin Receptor-Like Kinase 1 |
Gene, Accession # | UniProt: P37023 |
Catalog # | abx033694 |
Price | please inquire |
Order / More Info | Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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