Superoxide Dismutase 2 (SOD2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Superoxide Dismutase 2 (SOD2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SOD2 Antibody is a Rabbit Polyclonal antibody against SOD2. The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. The SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrix. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer?s disease, Parkinson?s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Polymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans. |
| Immunogen | Recombinant protein of human SOD2. |
| Other Names | SOD2, IPOB, MNSOD, MVCD6, Superoxide dismutase [Mn], mitochondrial, Superoxide dismutase [Mn] mitochondrial, superoxide dismutase 2 mitochondrial, IPO-B, Mn-SOD, SOD2, SOD2, SOD2, SOD2, IPOB, IPOB, IPOB, IPOB, MNSOD, MNSOD, MNSOD, MNSOD, MVCD6, MVCD6, MVCD6, MVCD6, Superoxide dismutase [Mn], Superoxide dismutase [Mn], Superoxide dismutase [Mn], Superoxide dismutase [Mn], mitochondrial, mitochondrial, mitochondrial, mitochondrial, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase [Mn] mitochondrial, superoxide dismutase 2 mitochondrial, superoxide dismutase 2 mitochondrial, superoxide dismutase 2 mitochondrial, superoxide dismutase 2 mitochondrial, IPO-B, IPO-B, IPO-B, IPO-B, Mn-SOD, Mn-SOD, Mn-SOD, Mn-SOD |
| Gene, Accession # | SOD2, Gene ID: 6648, UniProt: P04179 |
| Catalog # | abx001193 |
| Price | please inquire |
| Order / More Info | Superoxide Dismutase 2 (SOD2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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