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Antigenic Specificity | Renin (REN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | REN antibody is a Rabbit polyclonal antibody against REN. Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. |
Immunogen | Recombinant protein of human REN. |
Other Names | Angiotensinogenase, Renin, FLJ10761, REN, Angiotensinogenase, Angiotensinogenase, Angiotensinogenase , Angiotensinogenase , Renin, Renin, Renin , Renin , FLJ10761, FLJ10761, FLJ10761 , FLJ10761 , REN, REN, REN , REN |
Gene, Accession # | REN, Gene ID: 5972, UniProt: P00797 |
Catalog # | abx001335 |
Price | please inquire |
Order / More Info | Renin (REN) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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